Taking the opposite stance from my Grand Campaign manifesto:
<--- and posting it next to that picture
1. The Constitution was written with the intent of creating a "more perfect union" ... More perfect than the Articles of Confederation government. By June 26, 1788, eleven state conventions had ratified the Constitution. North Carolina and Rhode Island had not. At this point, the eleven states held a presidential election and started the new government. So by holding these conventions, the eleven states had seceded from the old government to start a new one.
2. Virginia and New York, in their resolutions of ratification, expressly asserted the right of the people of the states (their own people, and others by implication) to resume the powers they granted the national government under the Constitution, if those powers were ever used to their injury or oppression.
3. During the War of 1812, A convention of delegates from the New England states met at Hartford, CT ... to consider the question of seceding from the United States, as it was considered that national foreign policy was injuring those states. Their was no great public or official outcry about whether this group had a right to consider the question, or if they were traitors. Fortunately, the war ended before anything was decided.
4. After the United States was/were formed, as new citizens arrived (by birth or immigration), the natural tendency was to transfer the loyalty that had previously been given to individual states to the national government. This tendency was much stronger in areas with high immigration rates (the North and Northwest). With this transfer of loyalty went an expectation of the assumption of certain powers by the national government, and the setting of policies in the national interest. In those areas, it became fairly common during the 1850s to refer to "the United States" rather than "these United States".
5. Is Patrick Henry portrayed as a patriot or a traitor in American history books? He urged Virginians against ratifying the Constitution, foreseeing the possibility that it might be interpreted at the expense of "his people", and nobody of his generation fought harder for states rights.