Always wondered this. Can someone confirm that the game settings are applied only when the game is started? You can change the settings after the game starts or your PBEM partner has different settings, but that won't change that particular game.
What happens if you turn AI off, Does that impact a current game as well? If AI is on during during the start for a PBEM, would the AI only play if there is no other turn order. What about neutral factions????
Little things I've wondered about....